Au sein de l’IReSP, la personne recrutée aura pour mission d’assurer la coordination et/ou la réalisation des activités
administratives et financières de l’Institut en étroite relation avec la directrice adjointe administrative, et apportera un
appui aux actions de la direction et des membres de l’équipe.

It is clear that environmental exposures play a significant role in mental health and vulnerability to addiction. Certain pollutants, toxins, or excessive physical activity, can cause systemic inflammation and disrupt the immune system, interfering with neural circuits involved in impulse control, decision-making, and stress management. These alterations are known to be associated with an increased risk of depression and other mental disorders, which are risk factors for addiction. Opioids are often used for self-treatment of chronic pain and emotional disorders and they also continue to be the most effective pain relievers available in clinical practice. However, with chronic use, opioid pain relief is hindered by the development of analgesic tolerance, leading to a reduction in its effectiveness over time. Dose escalation is employed to overcome this reduced analgesia. Unfortunately, it also increases the risk of developing harmful and life-threatening side effects such as sleep disturbances or addiction. The links between the exposome (chemical, societal) and opioid addiction are an emerging area of research, suggesting that exposure to certain factors can influence the development and progression of addiction. The project to be developed should be in line with this theme.
The teaching project will be integrated into the neuroscience and neurotoxicology teaching offered at bachelor's and master's level. Within the Science Department of the Université de Paris Cité, there is in particular a master's program in neuroscience in which a significant part of the teaching can be delivered. We also have a master in Toxicology and teaching on the opioid epidemy and its toxic mechanisms would be of great benefit to our students. There is also a need to at least some introductory teaching on these issues at the bachelor level. Furthermore, larger scale teaching to inform citizens will be undertaken for example through public conferences or open online citizen teaching as developed in our university.

Premier centre de lutte contre le cancer en Europe, recrute un Biostatisticien, au sein du Bureau de Biostatistique et d’Epidémiologie. Le Bureau de Biostatistique et d’Epidémiologie conçoit et analyse de nombreux essais internationaux de phase I à phase III, des études observationnelles et des méta-analyses.
Plus d'informations sur les missions et la formation requise dans la fiche de poste en pdf ci-après